Undergraduate Education

Dr. Natoli earned her Bachelor of Science from The College of William & Mary (1997–2001), with a focus on biology and economics. Her undergraduate education provided a strong foundation in the biological sciences and prepared her for advanced medical training.

Medical School

Dr. Natoli earned her Doctor of Medicine from Upstate Medical University in Syracuse, New York (2001–2005). Her medical school training provided comprehensive preparation in clinical medicine and surgical fundamentals, establishing the foundation for her future specialization in plastic and reconstructive surgery.

Residency Training

Following medical school, Dr. Natoli completed a combined Plastic and Reconstructive Surgery Residency at Penn State Hershey Medical Center (2005–2010), where she served as Chief Resident during her final year of training. Her residency provided extensive experience across all aspects of plastic surgery, including aesthetic procedures, complex reconstructive surgery, microsurgery, and advanced surgical problem-solving.

Fellowship Training

Dr. Natoli completed an advanced Fellowship in Microsurgical Plastic and Reconstructive Surgery at the University of Pennsylvania in Philadelphia (2010–2011), one of the nation’s premier centers for microsurgical training. During her fellowship, she trained at Fox Chase Cancer Center in Philadelphia and Chang Gung Memorial Hospital at Linkou in Taiwan, gaining specialized expertise in autologous breast reconstruction and advanced microsurgical techniques. As a surgical team member, she participated in the planning and development of the hand transplant program at the University of Pennsylvania, further expanding her expertise in complex microsurgical reconstruction.

Board Certification and Professional Credentials

Dr. Natoli is board-certified by the American Board of Plastic Surgery (certified 2012) and holds the distinction of Fellow of the American College of Surgeons (FACS). Board certification and fellowship status demonstrate that Dr. Natoli has met rigorous standards of knowledge, clinical competency, and ethical practice—and maintains ongoing commitment to professional excellence through continuing education and recertification.

Dr. Natoli maintains active membership in leading professional organizations dedicated to advancing plastic surgery and microsurgical innovation:

• American Society of Plastic Surgeons (ASPS): The premier organization of board-certified plastic surgeons committed to advancing the science and art of plastic surgery
• American Society of Reconstructive Microsurgery (ASRM): A specialized organization dedicated to advancing microsurgical techniques and complex reconstructive procedures
• American College of Surgeons (ACS): A prestigious organization dedicated to improving the quality of care for surgical patients through education, advocacy, and professional standards
• North Eastern Society of Plastic Surgeons: Active member contributing to regional advancement of plastic surgical practice
• Association of Women Surgeons: Active member supporting women in surgical specialties
• Robert H. Ivy Society: Resident member of this prestigious surgical organization
• Nassau Surgical Society: Candidate member contributing to local surgical community

These memberships reflect Dr. Natoli’s dedication to staying current with the latest advances in plastic surgery, microsurgery, and reconstructive techniques, while maintaining the highest standards of clinical practice.

Specialized Microsurgical Expertise

Dr. Natoli has spent more than 15 years providing advanced plastic and reconstructive surgery to patients throughout New York City and Long Island. Her clinical experience encompasses specialized expertise in:

Breast Reconstruction:

• Autologous breast reconstruction using microsurgical techniques (DIEP flap, SIEA flap, TUG flap)
• Microsurgical free tissue transfer for complex breast reconstruction
• Implant-based breast reconstruction
• Oncoplastic breast surgery for cancer patients
• Breast revision and secondary reconstruction procedures
• Natural breast reconstruction with emphasis on aesthetic refinement and tissue preservation

Cosmetic Breast Surgery:

• Breast augmentation
• Breast reduction
• Breast lift and reshaping procedures
• Fat grafting for breast enhancement and refinement
• Gynecomastia

Body Contouring:

• Abdominoplasty (tummy tuck)
• Brachioplasty (arm lift)
• Labiaplasty
• Liposuction
• Thighplasty

Gender-Affirming Surgery:

• Facial feminization procedures
• Transmasculine top surgery
• Transfeminine breast augmentation
• Comprehensive gender-affirming surgical planning and care

Facial Rejuvenation:

• Fat grafting and volume restoration
• Facial contouring and refinement

Reconstructive Surgery:

• Microvascular reconstruction
• Complex wound reconstruction
• Trauma and burn reconstruction

Surgical Expertise and Innovation

Dr. Natoli’s specialized training in microsurgical techniques at the University of Pennsylvania, combined with international experience at Chang Gung Memorial Hospital in Taiwan, has established her as an expert in autologous breast reconstruction. Her focus on natural-looking results and preservation of tissue function reflects her commitment to advancing the field of microsurgical reconstruction and delivering outcomes that enhance both aesthetics and quality of life.

Dr. Natoli has pursued specialized training in the Preservé™ Breast Augmentation Method, a sophisticated surgical approach that prioritizes preservation of native breast tissue and long-term aesthetic stability. This advanced technique represents a refinement in modern breast enhancement, designed to achieve beautiful results while respecting the breast’s natural anatomy and function.
The Preservé™ methodology integrates precision surgical planning with Motiva SmoothSilk® Ergonomix2® implants and specialized instrumentation to minimize tissue disruption and optimize implant positioning. The technique employs gentle tissue elongation rather than aggressive dissection, an approach intended to preserve breast sensation, maintain natural softness, and support durable structural integrity over time.

Dr. Natoli selectively applies the Preservé™ method based on each patient’s individual anatomy, aesthetic objectives, and clinical suitability. Her training in this advanced technique underscores her commitment to offering patients access to cutting-edge surgical innovations while maintaining rigorous evidence-based standards in cosmetic breast surgery.

Research and Academic Contributions

Dr. Natoli is an active researcher and educator with multiple peer-reviewed publications and academic presentations. Her research focuses on microsurgical reconstruction, breast reconstruction outcomes, and surgical innovation. Her scholarly contributions include:

Peer-Reviewed Publications:

• Natoli NB, Wu LC. Vascular Variations of the TUG Flap in Consideration for Breast Reconstruction. Ann Plast Surg. 2014 Jan 7. [Epub ahead of print]
• Patel SA, Pang JH, Natoli NB, Gallagher S, Topham N. Reliability of venous couplers for microanastomosis of the venae comitantes in free radial forearm flaps for head and neck reconstruction. J Reconstr Microsurg. 2013 Sep;29(7):433-6.
• Mirzabiegi MN, Au A, Jandali S, Natoli NB, Sbitany H, Serletti JM. Trials and Tribulations With the Inferior Gluteal Artery Perforator (IGAP). Plast Reconstr Surg. 2011 Dec;128(6):614e-24e.
• Natoli NB, Patel S, Gallagher S, Topham N, Devarajan K. Reliability of Venous Couplers for Microanastomosis of the Venae Comitantes in Free Radial Forearm Flaps. Presented at WSRM: June 2011, Helsinki, Finland.
• Mirzabiegi MN, Au A, Jandali S, Natoli NB, Sbitany H, Serletti JM. Trials and Tribulations with the Inferior Gluteal Artery Perforator (IGAP) Flap in Autologous Breast Reconstruction. Manuscript accepted to PRS, 2010.
• Vakharia K, Natoli N, Johnson TS. “Stereolithography Aided Reconstruction of the Mandible.” Journal of Plastic and Reconstructive Surgery. Accepted for publication.
• Grunfeld R, Roghani R, Hazard SW, Hancey J, Natoli N, Noone R, Ehrlich HP, Mackay DR, Miraliakbari R. “Temporal Differences In Fibroblast Function And Cytokine Levels In Acute And Chronic VAC®-Treated Wounds.” Journal of Plastic and Reconstructive Surgery. Vol 120 Number 1S July 2007.
• Grunfeld R, Roghani R, Hazard SW, Hancey J, Natoli N, Noone R, Ehrlich HP, Mackay DR, Miraliakbari R. “The Evaluation Of Vac® Wound Fluid From Diabetic And Non-Diabetic Wounds: Levels Of VEGF, II-1, EDA-Fibronectin, Collagen, Correlation With Fibroblast Migration.” Journal of Plastic and Reconstructive Surgery. Vol 120 Number 1S July 2007.
• Roghani R, Grunfeld R, Hazard SW, Hancey J, Natoli N, Ehrlich HP, Mackay DR, Miraliakbari R. “Effects of Diabetes on IL-1 in VAC-Treated Wounds.” Journal of Surgical Research 137(2): 293, February, 2007.

Conference Presentations and Abstracts:

• Natoli, NB MD, Wu, LC MD. “Vascular Variations of the TUG Flap: Considerations for Breast Reconstruction.” Abstract presented at ASRM 2012 and NESPS 2011.
• Natoli, NB MD, Patel, S MD, Gallagher, S MD, Topham, N MD, Devarajan, K. “Reliability of Venous Couplers for Microanastomosis of the Venae Comitantes in Free Radial Forearm Flaps.” Abstract presented at WSRM (6/2010).
• Mirzabiegi, MN BS, Au A MD, Jandali S MD, Natoli NB MD, Sbitany H MD, Serletti JM MD FACS. “Trials and Tribulations With the Inferior Gluteal Artery Perforator (IGAP) Flap in Autologous Breast Reconstruction.” Presented at WSRM, Joint Annual Meeting of the Ohio Valley & Robert Ivy Society, and EURAPS. Manuscript submitted to PRS.
• Natoli, NB MD, Leber, D MD. “Revisiting the Role of the Tail of the Helix in Otoplasty.” Presented at Penn State Research Day.
• Natoli, NB MD, Hazard, SW MD, Neves, RI MD. “The Use of Bidirectional-barbed Knotless Absorbable Suture in Skin Oncology.” 117th World Congress on Melanoma & 5th Congress of the European Association of Dermato-Oncology (EADO) Vienna Austria, May 2009.
• Natoli, NB MD, Johnson, TS MD. “Frequency of Peri-operative Blood Transfusions in Free Tissue Transfer, A Single Centers Experience.” Abstract submitted to NESPS. Presented at Penn State Research Day, May 2009.
• Natoli, NB MD, Grunfeld, R BA, Roghani, R BA, Noone, R BA, Hancey, J MD, Hazard SW MD, Zelones, J BA, Ehrlich, HP PhD, Mackay, DR MD, Mirali R. “Vacuum-Assisted Closure Therapy of Diabetic versus Non-Diabetic Wounds: VEGF Expression and Wound Healing.” Presented at Robert H. Ivy Society of Plastic Surgeons meeting. Philadelphia, PA 2008. Presented at Penn State Diabetes Research Retreat. State College, PA 2008.
• Noone RH, Grunfeld R, Natoli NB MD, Hazard SW, Zelones J, Morrow B, Hancey J, Ehrlich P, Mackay DR, and Miraliakbari R. “Understanding the Physiologic Process Behind VAC®: Comparison of Wound Healing Markers with Non-VAC® Treated Wounds.” Presented at American Society of Reconstructive Microsurgery. Los Angeles, CA. 2008.
• Roghani, R Grunfeld, SW Hazard, J Hancey, NB Natoli, R Noone, HP Ehrlich, DR Mackay, R Miraliakbari. “Effect of Diabetes on IL-1β in VAC®-Treated Wounds.” Presented at the Academic Surgical Congress. Phoenix, AZ. 2007.
• Miraliakbari R, Mackay DR, Ehrlich HP, Grunfeld R, Roghani R, Hazard SW, Hancey J, Natoli NB MD: “The Evaluation Of VAC® Wound Fluid From Diabetic And Non-Diabetic Wounds: Levels Of VEGF, Il-1, Eda-Fibronectin, Collagen, Correlation With Fibroblast Migration.” American Association of Plastic Surgeons, 86th Annual Meeting, Coeur d’Alene, Idaho. 2007.
• Grunfeld R, Roghani R, Hazard SW, Hancey J, Natoli NB MD, Noone R, Ehrlich HP, Mackay DR, Miraliakbari R: “Temporal Differences In Fibroblast Function And Cytokine Levels In Acute And Chronic Vac®-Treated Wounds.” Presented at the 52nd Annual Meeting of the Plastic Surgery Research Council. Stanford, CA. 2007.
• Grunfeld R, Zelones J, Hazard SW, Hancey JM, Natoli NB MD, Noone R, Ehrlich HP, Mackay DR, Miraliakbari R: “The Evaluation Of VAC® Wound Fluid From Diabetic And Non-Diabetic Wounds: Levels Of Vegf, Il-1, Eda-Fibronectin, Collagen, Correlation With Fibroblast Migration.” Plastic Surgery Research Council 52nd Annual Meeting of the PSRC. Stanford, CA. 2007.
• Natoli, NB MD, Lee, M BS, Ehrlich, PH PhD. “Fibroblast Orientation, Migration and Vanadate Therapy in Fibrin.” Presented at Ivy Society Annual Meeting. Pittsburgh, PA 2006.
• Natoli, NB BS, Katz, D MD, Loftus, J MD. “Carpal Instability and Dislocations. Isolating Contributions of Specific Ligaments & Capsular Structures to Joint Stability Under Mechanical Stress Simulation.” Upstate Medical University Research Day, 2004.

Research Grants:

Dr. Natoli has contributed to significant research initiatives, including:

• GCRC Grant Support (HY97-061EP). (NIH Grant M01-RR10732 & RR016499). Performing cytokine and growth factor array analysis, transport of fluids, and statistical analysis. Co-investigators: Reza Miraliakbari MD, Jason Hancey, MD, Sprague W Hazard, MD, Noël Natoli, MD, Robert Grunfeld, BA, Justin Zelones BS, Donald R Mackay, MD, H Paul Ehrlich, PhD.
• Surgery Feasibility Grant $16,000 – Correlation of Human Wound Closure with Changes in Cytokine Levels in Wound Fluid. Co-investigators: Reza Miraliakbari MD, Jason Hancey, MD, Sprague W Hazard, MD, Noël Natoli, MD, Robert Grunfeld, BA, Justin Zelones BS, Donald R Mackay, MD, H Paul Ehrlich, PhD.

Her commitment to advancing surgical knowledge through research and education reflects her dedication to improving patient outcomes and contributing to the broader field of plastic and reconstructive surgery.